Modelling Geographic Atrophy Using Human Induced Pluripotent Stem Cells

Screening of CRISPR/cas base editors to target the AMD high-risk Y402H complement factor H variant

MTN Tran, MKNM Khalid, A Pébay, AL Cook, HH Liang, RCB Wong, JE Craig, GS Liu, SS Hung, AW Hewitt

2019-01-01

Purpose: To evaluate the efficacy of using a CRISPR/Cas-mediated strategy to correct a common high-risk allele that is associated ..